Stadium: Estadio Villa Concha Round: 4
| Colombia - Liga - Dames | 2022/03/15 20:00 | Deportivo Pereira - Dames v CD Real Santander - Dames | L | 2-1 |
| Colombia - Liga - Dames | 2023/02/12 00:30 | CD Real Santander - Dames v Junior - Dames | D | 1-1 |
| Colombia - Liga - Dames | 2023/02/05 23:00 | Deportivo Cali - Dames v CD Real Santander - Dames | L | 2-0 |
| Colombia - Liga - Dames | 2022/05/09 19:00 | La Equidad - Dames v CD Real Santander - Dames | L | 4-1 |
| Colombia - Liga - Dames | 2022/05/05 16:00 | CD Real Santander - Dames v America de Cali - Dames | L | 1-5 |
| Colombia - Liga - Dames | 2022/05/01 20:00 | Deportes Tolima - Dames v CD Real Santander - Dames | L | 3-0 |
| Colombia - Liga - Dames | 2022/04/17 18:00 | CD Real Santander - Dames v Internacional FC de Palmira - Dames | L | 1-4 |
| Colombia - Liga - Dames | 2022/04/13 20:00 | Llaneros - Dames v CD Real Santander - Dames | L | 6-1 |
| Colombia - Liga - Dames | 2022/04/10 16:00 | Atletico Bucaramanga - Dames v CD Real Santander - Dames | L | 2-0 |
| Colombia - Liga - Dames | 2023/02/25 19:00 | Deportivo Pereira - Dames v Deportes Tolima - Dames | W | 2-1 |
| Colombia - Liga - Dames | 2023/02/12 21:00 | Boyaca Chico - Dames v Deportivo Pereira - Dames | W | 1-2 |
| Colombia - Liga - Dames | 2023/02/04 19:00 | Deportivo Pereira - Dames v Independiente Medellin - Dames | D | 2-2 |
| Colombia - Liga - Dames | 2022/05/26 01:00 | America de Cali - Dames v Deportivo Pereira - Dames | L | 2-0 |
| Colombia - Liga - Dames | 2022/05/22 18:00 | Deportivo Pereira - Dames v America de Cali - Dames | D | 0-0 |
| Colombia - Liga - Dames | 2022/05/19 00:00 | Independiente Medellin - Dames v Deportivo Pereira - Dames | D | 0-0 |
| Colombia - Liga - Dames | 2022/05/15 16:00 | Deportivo Pereira - Dames v Independiente Medellin - Dames | W | 1-0 |
| Colombia - Liga - Dames | 2022/05/09 21:00 | Deportivo Pereira - Dames v Deportivo Cali - Dames | W | 2-1 |